BackgroundIn the Canadian Alliance for Healthy Hearts and Minds (CAHHM) cohort, participants underwent magnetic resonance imaging (MRI) of the brain, heart, and abdomen, that generated incidental findings (IFs). The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants (...) (mean age 58 ± 9 years, 54% women) were recruited with a follow-up questionnaire administered to 909 participants (40% response rate) at 1-year. The CAHHM policy followed a restricted approach, whereby routine feedback on IFs was not provided. Only IFs of severe structural abnormalities were reported.ResultsSevere structural abnormalities occurred in 8.3% (95% confidence interval 7.7–8.9%) of participants, with the highest proportions found in the brain (4.2%) and abdomen (3.1%). The majority of participants (97%) informed of an IF reported no change in quality of life, with 3% of participants reporting that the knowledge of an IF negatively impacted their quality of life. Furthermore, 50% reported increased stress in learning about an IF, and in 95%, the discovery of an IF did not adversely impact his/her life insurance policy. Most participants (90%) would enrol in the study again and perceived the MRI scan to be beneficial, regardless of whether they were informed of IFs. While the implications of a restricted approach to IF management was perceived to be mostly positive, a degree of diagnostic misconception was present amongst participants, indicating the importance of a more thorough consent process to support participant autonomy.ConclusionThe management of IFs from research MRI scans remain a challenging issue, as participants may experience stress and a reduced quality of life when IFs are disclosed. The restricted approach to IF management in CAHHM demonstrated a fair fulfillment of the overarching ethical principles of respect for autonomy, concern for wellbeing, and justice. The approach outlined in the CAHHM policy may serve as a framework for future research studies.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/nct02220582. (shrink)

In the present research, we examine the relation between leader mindfulness and employee performance through the lenses of organizational justice and leader-member relations. We hypothesize that employees of more mindful leaders view their relations as being of higher leader-member exchange quality. We further hypothesize two mediating mechanisms of this relation: increased interpersonal justice and reduced employee stress. In other words, we posit that employees of more mindful leaders feel treated with greater respect and experience less stress. Finally, we predict that (...) LMX quality serves as a mediator linking leader mindfulness to employee performance—defined in terms of both in-role and extra-role performance. Across two field studies of triadic leader-employee-peer data and dyadic leader–employee data, we find support for this sequential mediation model. We discuss implications for theorizing on leadership, organizational justice, business ethics, LMX, and mindfulness, as well as practical implications. (shrink)

This article presents a computational model of the learning of diagnostic knowledge, based on observations of human operators engaged in real-world troubleshooting tasks. We present a model of problem solving and learning in which the reasoner introspects about its own performance on the problem-solving task, identifies what it needs to learn to improve its performance, formulates learning goals to acquire the required knowledge, and pursues its learning goals using multiple learning strategies. The model is implemented in a computer system which (...) provides a case study based on observations of troubleshooting operators and protocol analysis of the data gathered in the test area of an operational electronics manufacturing plant. The model not only addresses issues in human learning, but, in addition, is computationally justified as a uniform, extensible framework for multistrategy learning. (shrink)

The September 2006 military coup against the Thaksin government in Thailand has had a profound impact on Thai politics. It has arrested the process of democratic consolidation that was set in motion in the country in the 1990s. Although many of Thaksin's policies lacked the spirit of democratic governance, he was democratically elected and was ousted from power unconstitutionally. The entire tenure of Thaksin has brought to the fore two deep cleavages in Thailand. The first of these is the deep (...) divide between the rural and urban electoral constituencies. The former provided a major vote bank with little bearing on the dispersion of power and resources that was effectively dominated by the latter. Thaksin and his populist policies effectively undermined the urban electorate and strengthened the rural constituency. The second and perhaps structurally more significant tension is that which has developed between the new business elite and the old establishment elite that comprise the monarchy, military, and the bureaucracy. This old elite has been at the forefront of displacing Thaksin through its fear of loss of control over the domestic political process. The drawn out confrontation that has spawned two social movements has significantly raised the country's political temperature and there is the real potential for the situation to deteriorate into violence. Despite these changes, a number of continuities unique to the Thai political situation continue to obtain as well. (shrink)

On the life and works of Sarvepalli Radhakrishnan, 1888-1975, Indian philosopher and statesman.

In the context of Kolmogorov's algorithmic approach to the foundations of probability, Martin‐Löf defined the concept of an individual random sequence using the concept of a constructive measure 1 set. Alternate characterizations use constructive martingales and measures of impossibility. We prove a direct conversion of a constructive martingale into a measure of impossibility and vice versa such that their success sets, for a suitably defined class of computable probability measures, are equal. The direct conversion is then generalized to give a (...) new characterization of constructive dimensions, in particular, the constructive Hausdorff dimension, the constructive packing dimension, and their generalizations, the constructive scaled dimension and the constructive scaled strong dimension (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim). (shrink)

The paper seeks to argue that the feeling of being part of a larger whole, considered to be a major feature of spiritual experience in some traditions, amounts to a change in the way the self is pre-reflectively understood. Further, the paper argues that some recent developments in the study of cognition support the case for such a revision in self-conception, and this can be used to build up a secular understanding of spirituality. The paper proceeds by making use of (...) Abraham Maslow's account of peak experience along with some accounts of both ancient and contemporary forms of spirituality to argue that the feeling of being part of a larger whole amounts to a significant shift from the separative self-conception implicit in everyday behavior. Subsequently, it is argued that some extant theories on cognition point at the illusory nature of separative self-conception. (shrink)

The Hindu ethic of cow protectionism is legislatively interpreted in many Indian states through the criminalisation of cow slaughter, and beef consumption, obscuring dairying’s direct role in the butchery of spent female and unproductive male bovines. Cow milk, however, is celebrated as sacred in scriptural and ritual Hinduism, and mobilised by commercial dairying, as well as by right-wing Hindu groups to advance the idea of a Hindu Indian nation. In order to fully protect cows from the harms of human exploitation, (...) it is vital to problematise milk as a benign, rightful product for humans to consume, including its use in Hindu beliefs, rituals and identity. The paper applies feminist vegan critiques to two Hindu legends commonly invoked to promote milk consumption: the boy-god Krishna’s great love for butter and the mythology of the gods and demons churning the Ocean of Milk to attain ambrosia. These critiques unsettle the core relationship of the Hindu to the cow as a lactating mother and provoke the idea that the original sacred milk in Hinduism in fact is plant-based and vegan. (shrink)

Significant technological advancements over the last two decades have led to enhanced accessibility to computing devices and the Internet. Our society is experiencing an ever-growing integration of the Internet into everyday lives, and this has transformed the way we obtain and exchange information, communicate and interact with one another as well as conduct business. However, the term ‘Internet addiction’ has emerged from problematic and excessive Internet usage which leads to the development of addictive cyber-behaviours, causing health and social problems. The (...) most commonly used intervention treatments such as motivational interviewing, cognitive-behavioural therapy, and retreat or inpatient care mix a variety of psychotherapy theories to treat such addictive behaviour and try to address underlying psychosocial issues that are often coexistent with IA, but the efficacy of these approaches is not yet proved. The aim of this paper is to address the question of whether it is possible to cure IA with the Internet. After detailing the current state-of-the-art including various IA definitions, risk factors, assessment methods and IA treatments, we outline the main research challenges that need to be solved. Moreover, we propose an Internet-based IA Recovery Framework which uses AI to closely observe, visualize and analyse patient’s Internet usage behaviour for possible staged intervention. The proposal to use smart Internet-based systems to control IA can be expected to be controversial. This paper is intended to stimulate further discussion and research in IA recovery through Internet-based frameworks. (shrink)

Embodied approach to cognition has taken roots in cognitive studies with developments in diverse fields such as robotics, artificial life and cognitive linguistics. Taking cue from the metaphor of a Watt governor, this approach stresses on the coupling between the organism and the environment and the continuous nature of the cognitive processes. This results in questioning the viability of computational–representational understanding of mind as a comprehensive theory of cognition. The paper, after giving an overview of embodied approach based on some (...) examples from conceptual metaphor theory, looks into a special case of Orwell’s problem in cognitive science. The problem is that there is so much evidence for embodiment to be true, yet there is little understanding of the same. I shall try to solve this problem by pointing out that it is our inveterate habits of perceiving ourselves that makes the embodied approach appear implausible. Studies on free will as well as the importance of the unconscious in overall cognitive processing raise challenging questions on our self-conception. A revision in the self-conception in the light of these findings will pave the way for a better appreciation of the embodied approach to cognition. (shrink)

It is frequently demanded that AI-based Decision Support Tools (AI-DSTs) ought to be both explainable to, and trusted by, those who use them. The joint pursuit of these two principles is ordinarily believed to be uncontroversial. In fact, a common view is that AI systems should be made explainable so that they can be trusted, and in turn, accepted by decision-makers. However, the moral scope of these two principles extends far beyond this particular instrumental connection. This paper argues that if (...) we were to account for the rich and diverse moral reasons that ground the call for explainable AI, and fully consider what it means to “trust” AI in a descriptively rich sense of the term, we would uncover a deep and persistent tension between the two principles. For explainable AI to usefully serve the pursuit of normatively desirable goals, decision-makers must carefully monitor and critically reflect on the content of an AI-DST’s explanation. This entails a deliberative attitude. Conversely, calls for trust in AI-DSTs imply the disposition to put questions about their reliability out of mind. This entails an unquestioning attitude. As such, the joint pursuit of explainable and trusted AI calls on decision-makers to simultaneously adopt incompatible attitudes towards their AI-DST, which leads to an intractable implementation gap. We analyze this gap and explore its broader implications: suggesting that we may need alternate theoretical conceptualizations of what explainability and trust entail, and/or alternate decision-making arrangements that separate the requirements for trust and deliberation to different parties. (shrink)

This article argues that gaushalas, or cow shelters, in India are mobilized as sites of Hindutva or Hindu ultranationalism, where it is a “vulnerable” Hindu Indian nation—or the “Hindu mother cow” as Mother India—who needs “sanctuary” from predatory Muslim males. Gaushalas are rendered spaces of production of cows as political, religious, and economic capital, and sustained by the combined and compatible narratives of “anthropatriarchy” and Hindu patriarchy. Anthropatriarchy is framed as the human enactment of gendered oppressions upon animal bodies, and (...) is crucial to sustaining all animal agriculture. Hindu patriarchy refers to the instrumentalization of female and feminized bodies as “mothers” and cultural guardians of a “pure” Hindu civilization. Both patriarchies commodify bovine motherhood and breastmilk. which this article frames as a feminist issue. Through empirical research, this article demonstrates that gaushalas generally function as spaces of exploitation, incarceration, and gendered violence for the animals. The article broadens posthumanist feminist theory to illustrate how bovine bodies, akin to women's bodies, are mobilized as productive, reproductive, and symbolic capital to advance Hindu extremism and ultranationalism. It subjectifies animal bodies as landscapes of nation‐making using ecofeminism and its subfield of vegan feminism. (shrink)

Integrated information theory of consciousness proposes an identity between its causal structure and phenomenology. Through this assertion, IIT aims to explain consciousness by prioritizing first-person experience. However, despite its phenomenology-first stance, developments in IIT have overlooked temporality. As such, we argue that at present IIT’s phenomenological analysis is incomplete. In this critique, we show how IIT takes a non-identical illusionist stance towards the experiences of continuity, flow, and extent of our experiences. Moreover, in isolating temporal grains of experience to a (...) single timescale, IIT misses out on capturing the multi-scale nested nature of temporal phenomena. Hence, we contend that IIT needs an axiom for time, through which its causal structure can be refined to account for temporal experiences. Here, we propose an axiom to address these concerns. We conclude by discussing how IIT may need to be revised if our concerns hold true. (shrink)

Humans tend to seek their identity as entities existing over a period of time by making narratives. The paper argues that seeking diachronic self-identity through narratives or stories results in the self-experience being one of separation or alienation from the real world. This happens because language is primarily a form of secondary representation, and the means by which we attempt to find identity often appear in the form of narratives. The dominance of the metaphor of life as a journey shows (...) this. The remedy is to reduce the hold of narrativity by making self-experience fundamentally episodic. (shrink)

We examined proactive and reactive control effects in the context of task-relevant happy, sad, and angry facial expressions on a face-word Stroop task. Participants identified the emotion expressed by a face that contained a congruent or incongruent emotional word. Proactive control effects were measured in terms of the reduction in Stroop interference as a function of previous trial emotion and previous trial congruence. Reactive control effects were measured in terms of the reduction in Stroop interference as a function of current (...) trial emotion and previous trial congruence. Previous trial negative emotions exert greater influence on proactive control than the positive emotion. Sad faces in the previous trial resulted in greater reduction in the Stroop interference for happy faces in the current trial. However, current trial angry faces showed stronger adaptation effects compared to happy faces. Thus, both proactive and reactive control mechanisms are dependent on emotional valence of task-relevant stimuli. (shrink)

Unconscious thought theory (UTT) states that all information is taken into account and the attributes are weighted optimally resulting in better decisions in complex decision problems during unconscious thought. Very few studies have investigated the actual amount of information processed in the unconscious thought condition. We hypothesized that only a small subset of information might be considered during unconscious thought (like conscious thought). To test this possibility and to explore the way attribute information is selected and combined, we performed computer (...) simulations on the datasets used by previous researchers. The simulations showed that considering a small subset (3-4) of attributes, yields results comparable to previous studies. There is no need to posit infinite capacity in the unconscious thought condition. The results also suggest that weight information is used for attribute selection that could potentially explain the difficulties in replicating the deliberation-without-attention effect. (shrink)

Despite the rapid adoption of technology in human resource departments, there is little empirical work that examines the potential challenges of algorithmic decision-making in the recruitment process. In this paper, we take the perspective of job applicants and examine how they perceive the use of algorithms in selection and recruitment. Across four studies on Amazon Mechanical Turk, we show that people in the role of a job applicant perceive algorithm-driven recruitment processes as less fair compared to human only or algorithm-assisted (...) human processes. This effect persists regardless of whether the outcome is favorable to the applicant or not. A potential mechanism underlying algorithm resistance is the belief that algorithms will not be able to recognize their uniqueness as a candidate. Although the use of algorithms has several benefits for organizations such as improved efficiency and bias reduction, our results highlight a potential cost of using them to screen potential employees during recruitment. (shrink)

This article argues that there is no performative self-contradiction involved in reports of selfless consciousness, at least in the non-pathological sense of the term. This is because what is central to the experience of selfless consciousness is a different kind of relation of the self with the rest of the world and, therefore, it is not a case of dissolution or decimation of the self. Such an understanding of selflessness can easily distinguish spiritual selflessness from pathological forms such as depersonalisation. (...) This article seeks to provide an explanation for why reports are made of there being no self or subjectivity by appealing to the notion of attentional saliency. (shrink)

The notion of epistemic injustice has become an important topic of inquiry in recent times. It refers to the injustice committed to a person when her claim to knowledge is not given due consideration. This article argues that there are two major sources of epistemic injustice: One is the dominating tendencies present in us, and the other is susceptibility to cognitive biases and distortions. When societies become more complex, injustice increases and one can see countless instances of epistemic injustice in (...) everyday life. To reduce epistemic injustice, one has to tackle both sources. Increasing cooperative behaviour is the key in this regard which, in turn, may require revisiting the way the self is automatically understood. (shrink)

The purpose of this article is to unearth the dimensions of quality of work life and work–life balance and to find the impact of the quality of work life on work–life balance. Data have been gather...

The coupling of protein synthesis and folding is a crucial yet poorly understood aspect of cellular protein folding. Over the past few years, it has become possible to experimentally follow and define protein folding on the ribosome, revealing principles that shape co‐translational folding and distinguish it from refolding in solution. Here, we highlight some of these recent findings from biochemical and biophysical studies and their potential significance for cellular protein biogenesis. In particular, we focus on nascent chain interactions with the (...) ribosome, interactions within the nascent protein, modulation of translation elongation rates, and the role of mechanical force that accompanies nascent protein folding. The ability to obtain mechanistic insight in molecular detail has set the stage for exploring the intricate process of nascent protein folding. We believe that the aspects discussed here will be generally important for understanding how protein synthesis and folding are coupled and regulated. (shrink)

Contributed research papers on various aspects of Hindu philoosphy.

Search engines are important contemporary sources of information and contribute to shaping our beliefs about the world. Each time they are consulted, various algorithms filter and order content to show us relevant results for the inputted search query. Because these search engines are frequently and widely consulted, it is necessary to have a clear understanding of the distinctively epistemic role that these algorithms play in the background of our online experiences. To aid in such understanding, this paper argues that search (...) engine algorithms are providers of “bent testimony”—that, within certain contexts of interactions, users act as if these algorithms provide us with testimony—and acquire or alter beliefs on that basis. Specifically, we treat search engine algorithms as if they were asserting as true the content ordered at the top of a search results page—which has interesting parallels with how we might treat an ordinary testifier. As such, existing discussions in the philosophy of testimony can help us better understand and, in turn, improve our interactions with search engines. By explicating the mechanisms by which we come to accept this “bent testimony,” our paper discusses methods to help us control our epistemic reliance on search engine algorithms and clarifies the normative expectations one ought to place on the search engines that deploy these algorithms. (shrink)

Jockusch showed that 2-generic degrees are downward dense below a 2-generic degree. That is, if a is 2-generic, and $0 < {\bf{b}} < {\bf{a}}$, then there is a 2-generic g with $0 < {\bf{g}} < {\bf{b}}.$ In the case of 1-generic degrees Kumabe, and independently Chong and Downey, constructed a minimal degree computable from a 1-generic degree. We explore the tightness of these results.We solve a question of Barmpalias and Lewis-Pye by constructing a minimal degree computable from a weakly 2-generic (...) one. While there have been full approximation constructions of ${\rm{\Delta }}_3^0$ minimal degrees before, our proof is rather novel since it is a computable full approximation construction where both the generic and the minimal degrees are ${\rm{\Delta }}_3^0 - {\rm{\Delta }}_2^0$. (shrink)

This work contributes to the program of studying effective versions of “almost-everywhere” theorems in analysis and ergodic theory via algorithmic randomness. Consider the setting of Cantor space {0,1}N with the uniform measure and the usual shift. We determine the level of randomness needed for a point so that multiple recurrence in the sense of Furstenberg into effectively closed sets P of positive measure holds for iterations starting at the point. This means that for each k∈N there is an n such (...) that n,2n,…,kn shifts of the point all end up in P. We consider multiple recurrence into closed sets that possess various degrees of effectiveness: clopen, Π10 with computable measure, and Π10. The notions of Kurtz, Schnorr, and Martin-Löf randomness, respectively, turn out to be sufficient. We obtain similar results for multiple recurrence with respect to the k commuting shift operators on {0,1}Nk. (shrink)